The Power of Outsourcing in Early through Preclinical Drug Development

Sept. 9, 2010 in La Jolla, CA

4:30 p.m. to 9:00 p.m
Hyatt Regency
La Jolla, CA

Register today – seating is limited!

The Power of Outsourcing in Early through Preclinical Drug Development

Mark your calendar and plan to join us for a one day Symposium featuring nine senior level pharmaceutical and biotechnology industry speakers in a keynote address, case study presentations and discussions covering hot topics and end-to-end solutions across the drug-development spectrum. The presentations will explore a number of issues related to “Early through Preclinical Drug Development” and features internationally recognized experts in drug discovery and development discussing topics including:

Keynote Topic:
The objective of this presentation is to provide biotech companies the moste effective ways of outsourcing pre-clinical testing. Theses will include identifying the criteria for choosing the appropriate contract lab based on its history, capabilities, expertise, and finally making a choice between science and quality of the product versus cost.

Panel Topics:

Medicinal Chemistry: IP generation, hit validation, lead optimization and solving tough synthetic problems

In Vitro Approaches for Organ Specific Toxicity Screening: A new in vitro approach designed to determine if a drug will cause adverse effects in liver, heart, or kidney. By incorporating a two cell model, organ specific toxicity endpoints, and markers of general cell health that it is possible to identify a drugs potential to cause liver, heart, or kidney toxicity

Challenges Associated with “Metabolomics”: The comprehensive, integrated analytical and data handling platform that provide a chemo-centric global metabolism analyses of biological systems. Presenting a specific case study describing the impact of this platform in a Drug Mechanism of Action Study

“Biologics,” or Large Molecules: Showcasing many significant ways in which the development process of a large molecule differs from that of traditional small molecules, including immune response, dose solution preparatory considerations, species-specific pharmacologic factors, and delivery methods

Chemistry, Manufacturing and Control (CMC): Formulation and analytical development topics along with early phase cGMP clinical supply manufacturing. The presentation will provide participants with the fundamentals needed to successfully implement an early stage CMC development process

Phase I Clinical Pharmacology and Early Clinical Research Studies: Cardiac safety, PK/PD, drug interaction and methodology studies. Incorporating pharmacogenetics and biomarkers into exploratory and proof of concept studies

Agenda:

4:00 p.m. – 5:00 p.m. Registration, Networking & Visiting Exhibit Hall: Complimentary cocktails and horsd’oeuvres will be served
5:00 p.m. – 8:30 p.m.: Panel Presentation
8:30 p.m. -9:00 p.m. Q&A
9:00 p.m. Adjourn

Keynote Speaker:

Ali Faqi, Ph.D., DVM, DABT – MPI

Panel Speakers:

David C. Zimmermann, CEO – Kalexsyn Inc.

James McKim, Ph.D., DABT – CSO, CeeTox Inc

John Ryals, Ph.D. – CEO, Metabolon

David McGee, Ph.D. – MPI

David Barnes, PhD – CSO, Velesco Pharmaceutical

Dean Knuth – CEO, Jasper Clinic

Grace M. Furman, Ph.D., DABT- CEO/President, Paracelsus, Inc.

Sylvie K. Sakata, PhD Senior Director
Pfizer Inc. La Jolla and St Louis
Lead External Research Solutions RCoE

Registration:

Begins on July 12th

There is no charge to attend this conference; however, advance registration is required and space is limited. Interested individuals can register online at IALSN’s website at www.ialsn.org

For advanced reservations, please contact Maryam Famourzadeh at mfamourzadeh@ialsn.org

Sponsorship levels:
Diamond ($1,000.00); Platinum ($400.00), Gold ($200.00), and Silver ($100.00)
To become a sponsor please email us at info@ialsn.org

For more info please visit
www.ialsn.org

http://iccvam.niehs.nih.gov/meetings/BiologicsWksp-2010/BiologicsWksp.htm

The email contact is: niceatm@niehs.nih.gov

26th International IFSCC (International Federation Societies of Cosmetic Chemists) Congress – Innovation & Responsibility: Cosmetics Forever

Sept. 20-23 in Buenos Aires, Argentina

Sept. 20-23, 2010
Sheraton Buenos Aires Hotel & Convention Center
Buenos Aires, Argentina

The 26th Congress in 2010 will be showcase for the presentation of research studies. These studies are representative of the high level attained by cosmetic science, which, on the foundations of innovation and responsibility, provides us with more effective, higher technology products, safer for both the consumer and the environment.

Dr. James McKim will be giving both an oral presentation and a poster at this Congress. The oral presentation, A New In Vitro Method for Identifying Skin Sensitizers and Predicting LLNA EC3 Values will be given Wed., Sept. 22 at 10am. The poster to be presented is Predicting Acute Oral Toxicity (LD50) with an In Vitro Cell-Based system. The poster will be displayed from Sept. 21-23.

Visit the IFSCC 2010 web site

Visit the ACT 2010 Annual Meeting and Call for Abstracts website.

AAPS – American Association of Pharmaceutical Scientists

Nov. 14-17, 2010 in New Orleans, LA

Every three to four years, the International Pharmaceutical Federation (FIP) organizes a Pharmaceutical Sciences World Congress (PSWC). Each year, the American Association of Pharmaceutical Scientists (AAPS) organizes the AAPS Annual Meeting and Exposition.

In 2010 FIP and AAPS will hold the PSWC and the Annual Meeting together in New Orleans, LA at the Morial Convention Center from November 14–18 (The expo runs from Nov. 14-17). The scientific theme is: Improving Global Health Through Advances in Pharmaceutical Sciences.

The joint meeting will include:
• A forum for the exchange of ideas and information about the sciences that the
organizations represent
• Continuing professional development for individual members and related professionals
• An introduction of the latest technological advances

Visit CeeTox at Booth 3204

Visit the AAPS website.

Society of Toxicology 2011

March 7-9, 2011 in Washington, DC

The Society of Toxicology (SOT) Annual Meeting is the largest toxicology meeting and exhibition in the world, attracting more than 6,500 scientists from industry, academia, and government from various countries around the globe. From the keynote address and special lectures, to a wide range of symposia sessions to continuing education courses that cover the basic and the advanced topics of the day, to the workshops, thematic sessions that complement the symposia, roundtables, poster sessions, and award presentations, SOT’s Annual Meeting has something for every attendee.

Look for CeeTox at Booth 307 at the SOT’s ToxExpo 2011 in Washington, DC, from March 7-9, 2011. SOT’s Annual Meeting is the forum to showcase toxicology’s novel discoveries.

Visit the ToxExpo 2011 website.

in-cosmetics 2011

March 29-31, 2011 in Milan, Italy

CeeTox will be exhibiting in Space B93 at in-cosmetics to be held at Fiera Milano, Milan, Italy March 29-31, 2011.

Staged annually in spring in a major European city, in-cosmetics brings together the world’s leading cosmetics suppliers, R&D, production and marketing specialists and showcases the most diverse range of new and innovative cosmetics ingredients and services. Offering a crucial insight into future scientific advances, emerging trends and regulations in an unrivaled educational program, in-cosmetics is the most comprehensive source of industry expertise and the most effective formula for developing business opportunities.

The Cosmetic Science Conference will be your opportunity to learn from an exciting new-line of industry experts.
Visit the in-cosmetics website.

IUTOX 2010 – XII International Congress of Toxicology

July 19-23, 2010 in Barcelona, Spain

IUTOX 2010 – XII International Congress of Toxicology
Palau de Congressos de Barcelona (Fira de Barcelona)
Barcelona, Spain

The International Congress of Toxicology (ICT) has been held triennially in various countries since its inaugural meeting in Toronto, Canada in 1977. Thirty-three years later, the Spanish Association of Toxicology (AETOX), together with the European Society of Toxicology (EUROTOX), will host ICT XII in Barcelona, Spain from July 19–23, 2010. With a focus on chemical safety and risk assessment, participants from academia, industry and the regulatory sector are expected to attend. A full week of programming is planned including key lectures, symposia, roundtables and the much anticipated, annual SOT-EUROTOX Debate. The Congress will also feature the IUTOX General Assembly and the backdrop of Barcelona is sure to add a very special cultural flavor and dimension to the meeting. While we will not be attending, CeeTox is a contributor to this Congress.

Visit the IUTOX web site

Visit the Sustainable Fragrances 2010 website.

in-cosmetics 2010

April 13-15, 2010 in Paris, France

CeeTox will be exhibiting in Space E114 in Hall 7 at in-cosmetics to be held at Porte de Versailles, Paris, France April 13-15, 2010.

Staged annually in spring in a major European city, in-cosmetics brings together the world’s leading cosmetics suppliers, R&D, production and marketing specialists and showcases the most diverse range of new and innovative cosmetics ingredients and services. Offering a crucial insight into future scientific advances, emerging trends and regulations in an unrivaled educational program, in-cosmetics is the most comprehensive source of industry expertise and the most effective formula for developing business opportunities.

The Cosmetic Science Conference will be your opportunity to learn from an exciting new-line of industry experts.
Visit the in-cosmetics website.

Society of Toxicology 2010

March 7-11, 2010 in Salt Lake City, Utah

The Society of Toxicology (SOT) Annual Meeting is the largest toxicology meeting and exhibition in the world, attracting more than 6,500 scientists from industry, academia, and government from various countries around the globe. From the keynote address and special lectures, to a wide range of symposia sessions to continuing education courses that cover the basic and the advanced topics of the day, to the workshops, thematic sessions that complement the symposia, roundtables, poster sessions, and award presentations, SOT’s Annual Meeting has something for every attendee.

We will be presenting the following four posters in the Exhibition Hall:

Abstract Number 111 Poster Board -127
March 8, 2010 from 9:30 AM to 12:30 PM
A New In Vitro Method For The Detection of Chemical Sensitizers: Combines Peptide Binding With ARE/EpRE-Linked Gene Expression

Abstract Number 105 Poster Board -121
March 8, 2010 from 9:30 AM to 12:30 PM
A New In Vitro Method For Identifying Chemical Mediated Respiratory Toxicity Using Multiple Endpoint Analysis and The Epi-Airway™ Model

Abstract Number 113 Poster Board -129
March 8, 2010 from 9:30 AM to 12:30 PM
Methods for Improving the Interpretation of In Vitro Endocrine Screening Data: Reducing False Negative and False Positive Results

Abstract Number 492 Poster Board -633
March 8, 2010 from 1:00 PM to 4:30 PM
Development and Characterization of Human and Mouse Primary Epithelial Cell Cultures For Assessing Arsenic Toxicity

Look for CeeTox at Booth 200 at the SOT’s ToxExpo 2010 in Salt Lake City, Utah, from March 7-11, 2010. SOT’s Annual Meeting is the forum to showcase toxicology’s novel discoveries.

Visit the ToxExpo 2010 website.

ACT – American College of Toxicology

Nov. 1-Nov. 3, 2009 in Palm Springs, CA

Join us for the 30th Annual Meeting of the American College of Toxicology (ACT) at the Wyndham Palm Springs. The mission of ACT is to educate, lead and serve professionals in industry, government and academia by promoting the exchange of information and perspectives on safety assessment and the application of new developments related to toxicology. CeeTox will be exhibiting at booth 115.

Visit the ACT 2009 Annual Meeting website.

2009 Cosmetic Science Expo

Oct. 27-29, 2009 in Newark, NJ

Looking for ways to meet with top scientists and R&D professionals in the cosmetic and personal care products industry? This is the place to be. The 2009 Cosmetic Science EXPO brings together industry suppliers and manufacturers in a smaller setting that is most conducive to making personal connections and doing business. CeeTox will be exhibiting at the Expo.

Visit the 2009 Cosmetic Science Expo website

The Cosmetic, Toiletry & Perfumery Association Ltd.

Oct. 14, 2009 at The Seligman Theatre, Royal College of Physicians, London, England

CTPA Seminar on the New EC Cosmetic Regulation

CTPA Members only

The CTPA is holding a one-day seminar on the new EC Cosmetics Regulation, re-cast from a directive, on 14 October 2009 at The Royal College of Physicians in London.

While the Regulation has yet to be officially published (delayed to October/November owing to jurist linguists/translation issues), CTPA and other industry experts are working in the Colipa Strategic Project Team Re-cast to develop industry guidance. This guidance will be shared with the European Commission and enforcement authorities to ensure a common understanding.

Syed Ahmed Mustafa, Director of Sales & Marketing for CeeTox, will give a presentation: Toxicology Testing 101, an introductory look at the history of testing, its application to the cosmetics industry, and the implications of current regulations.

Visit the CTPA seminar website

Webinar on Endocrine Disruptor Screening Program

Sept. 30, 2009

Smithers Viscient is hosting a free 90-minute Endocrine Disruptor Screening Program (EDSP) webinar on September 30, 2009 at 10am EST. Jeff Pregenzer, CeeTox Director of Endocrine Studies, will be the first speaker, presenting In vitro testing overview.

Please click below to register.

Endocrine Webinar registration

International Society of Regulatory Toxicology and Pharmacology

Sept. 9-10, 2009, National Institutes of Health (NIH), Lister Hill Auditorium, Bethesda, MD

The International Society of Regulatory Toxicology and Pharmacology (ISRTP) presents its 2009 Endocrine Workshop:

The Endocrine Disruptor Screening Program: What Can Screening Results Tell Us About Potential Adverse Endocrine Effects?
The ISRTP 2009 Endocrine Workshop will examine EPA’s proposed EDSP Tier 1 screening battery. EPA will soon require chemical manufacturers, specifically manufacturers and importers of pesticide active and inert ingredients, to screen specific products for potential endocrine activity using a predetermined set of screening assays developed under the Agency’s Endocrine Disruptor Screening Program (EDSP).

The goal of the ISRTP 2009 Endocrine workshop is to expand the dialogue among EPA, the regulated community, experts in endocrine testing and other interested parties for the purpose of developing appropriate guidance and procedures for interpreting and using EDSP screening data.
Experts will discuss the strengths and weaknesses of each assay and elucidate the potential uses of data generated by those assays. They will also examine how currently available data might be used to avoid duplicative screening. The workshop discussions will highlight data gaps, data needs and potential alternative screening and testing methods. Regulatory and legal experts will examine legal issues raised by the EDSP program and text orders. Attendees will include potential testing order recipients, lawyers, consultants and regulators.

Jeff Pregenzer, Director of Endocrine Studies at CeeTox, will be participate in an expert panel discussion on Incorporating Existing Data into the EDSP.

CeeTox will be sharing a display table with Smithers Viscient at the reception on Sept. 9. Please stop by and learn more about our in vitro testing capabilities.

Visit the ISRTP Workshop registration website

WC7 – Calling on Science

Aug. 30 - Sept. 3, 2009 in Rome, Italy

The World Congresses on Alternatives & Animal Use in the Life Sciences are the longest running series of international scientific conferences dedicated to the replacement reduction, and refinement (3Rs) of animal use in research and safety testing. These conferences have been held every 2-3 years since 1993 and have attracted a large international group of stakeholders and leading experts in the development and use of methods that replace, reduce, and/or refine (3Rs) animal-based laboratory methods.

Dr. James McKim will be presenting four posters at the 7th World Congress on Alternatives and Animal Use in the Life Sciences to be held in Rome, Italy at the Cavalieri Hilton Hotel Aug. 30 – Sept. 3, 2009.

“AN IN VITRO MODEL FOR ASSESSING THE EFFECTIVENESS OF ANTIOXIDANTS IN COSMETICS” — Poster 157.

“CULTURE, CHARACTERIZATION, AND IN VITRO TOXICITY OF ARSENIC IN MOUSE PRIMARY UROEPITHELIAL CELLS” — Poster 158

“IDENTIFYING RESPIRATORY TOXICITY USING THE EPIAIRWAY HUMAN 3-D MODEL COMBINED WITH MULTIPLE ENDPOINT ANALYSIS” — Poster 159.

“A NEW IN VITRO METHOD FOR IDENTIFYING SKIN SENSITIZERS AND PREDICTING LLNA EC3 VALUES” — Poster 160.

Visit us at Booth C14.

Visit the WC7 website

Endocrine Program Breakfast Seminar – August 12th in RTP

August 12, 2009 in Research Triangle Park, NC

Smithers Viscient is hosting a free half-day Endocrine Disruptor Screening Program (EDSP) seminar in Research Triangle Park, North Carolina on August 12th 2009.

At the Endocrine Program Breakfast Seminar and Networking Event (you’ll hear educational overviews of the ecotoxicology, in vitro, and in vivo toxicology testing requirements for the EDSP(, and you can participate in an open forum discussion about these requirements. Scientists specializing in each field of testing will discuss their experience with Tier 1 screening assays, and presenters will give comprehensive explanations of the prescribed endpoints for each assay. After the seminar, you’ll have an opportunity to network with future task force members.

Join us for a complimentary hot buffet breakfast at 8:15 am, before the presentations begin. Afterwards, stay for the Panel Discussion, where speakers will address specific questions about requirements for your particular substances.

To register for this free event, go to http://info.smithersviscient.com/endocrine-seminar.
Upon registering, you will receive an email with the complete agenda and directions to the seminar.

Endocrine Program Seminar Topics and Speakers
Endocrine Disruptor Screening Program overview, Ron Biever, Chief Scientific Officer, Smithers Viscient

In vivo testing overview, Susan Borghoff, PhD, DABT, Director, Investigative Toxicology Division, Integrated Laboratory Systems, Inc. (ILS)

Ecotoxicology testing overview, Arthur Putt, Technical Consultant, Springborn Smithers

In vitro testing overview, Jeff Pregenzer, Director of Endocrine Studies, CeeTox

Panel Discussion

We look forward to seeing you in Research Triangle Park!

Sustainable Fragrances for Cleaning Products Conference

June 3-5, 2009 in Washington D.C.

Dr. James McKim has been invited to present a special session at the Sustainable Fragrances for Cleaning Products Conference 2009 to be held at the Marriott Washington Hotel in Washington D.C. from June 3-5, 2009.

The conference will address the most salient issues facing this market, including definitions of “green” and “sustainable” that are meaningful for all constituent industries, and the creation of a list of criteria for “green” fragrances developed by the EPA’s DfE (Design for the Environment) program and RIFM, the Research Institute for Fragrance Materials.

Dr. McKim will discuss the science behind determining allergic response and sensitization to fragrance. He developed CeeTox’s novel in vitro screen SenCeeTox that tests for the potential to cause skin sensitization without the use of animals, demonstrating a high correlation to LLNA EC3 values, the current validated method.

Don’t miss this conference for presentations by industry experts on recent innovations, current research, plus the latest developments in “green” marketing.

Visit the Sustainable Fragrances for Cleaning Products Conference 2009 website.

NYSCC Suppliers’ Day

May 12-13, 2009 in Edison, NJ

Visit us at Booth 1231 at the New York Society of Cosmetic Chemists Suppliers’ Day at the New Jersey Convention and Exposition Center, Raritan Center, Edison, NJ May 12-13, 2009. We will be sharing the booth with SkinEthic.

The theme of this year’s show is Innovate for a Greener World. This will be your opportunity to discuss the latest innovations with technical, marketing, and business associates from around the world. The NYSCC Suppliers’ Day is one of the largest events of its kind in the world! Last year’s event drew over 4,000 chemists.

Visit the NYSCC Suppliers’ Day website.

in-cosmetics

April 21-23, 2009 in Munich, Germany

CeeTox will be exhibiting in Booth E860 in Hall A1 at in-cosmetics to be held at The New Munich Trade Fair Centre, Munich, Germany April 21-23, 2009.

Staged annually in spring in a major European city, in-cosmetics brings together the world’s leading cosmetics suppliers, R&D, production and marketing specialists and showcases the most diverse range of new and innovative cosmetics ingredients and services. Offering a crucial insight into future scientific advances, emerging trends and regulations in an unrivaled educational program, in-cosmetics is the most comprehensive source of industry expertise and the most effective formula for developing business opportunities.

The Cosmetic Science Conference will be your opportunity to learn from an exciting new-line of industry experts. Aimed at formulators, bench chemists and R&D specialists, the 2-day program will focus on “New Technologies in Cosmetics Formulation.”

Visit the in-cosmetics website.

Society Of Toxicology ToxExpo 2009

March 15-19, 2009 in Baltimore, MD

Look for CeeTox at Booth 1734 at the SOT’s ToxExpo 2009 in Baltimore, Maryland, from March 15 – 19, 2009. SOT’s Annual Meeting is the forum to showcase toxicology’s novel discoveries.

Don’t miss our special presentation on the next generation of testing for skin sensitization! CeeTox will host a break-out conference session A Novel In Vitro Method to Assess Skin Sensitization on Tuesday, March 17 from 2:45 p.m. to 3:45 p.m. in Room 337. NOTE-this session is exhibitor-hosted. Although not an official part of the SOT annual meeting scientific program, its presentation is permitted by the society. Seating is limited, so plan to arrive early.

Visit the ToxExpo 2009 website.

Cosmeceuticals Summit 2009

March 9-11, 2009 in Orlando, FL

Dr. James McKim will co-chair a full-day seminar on Utilizing In Vitro Data to Support REACH and the Cosmetics Directive for Safety Assessment on March 9, 2009. This seminar kicks off the Cosmeceuticals Summit 2009 at Rosen Plaza Hotel in Orlando, Florida, from March 9-11, 2009.

Dr. McKim will discuss how to use in vitro data to identify risk and evaluate efficacy with human reconstructed tissue models, and he will detail CeeTox’s new In Vitro Sensitization Panel of screens that assess corrosion, irritation, sensitization, genotoxicity, and phototoxicity.

On March 11, Dr. McKim will present a session at 11:45 a.m. on SenCeeTox, CeeTox’s new in vitro approach for determining skin sensitization that predicts LLNA EC3 values.

The Cosmeceutical Summit offers presentations by industry experts on recent innovations, current research, updates on regulatory standards, plus the latest developments in “green” marketing, antioxidants, anti-aging products, and much more.

Visit the Cosmeceuticals Summit 2009 website.

Molecular Medicine Tri-Conference

February 24-27, 2009 in San Francisco, CA

CeeTox’s Maryam Famourzadeh, business development manager for western North American, will attend the Molecular Medicine Tri-Conference at Moscone North Convention Center in San Francisco, California, from February 24-27, 2009. Maryam will network and advise clients on CeeTox’s latest developments to promote preclinical drug safety. The Tri-Conference is an annual networking and educational venue that brings more than 3,000 professionals together. This year’s theme is “Shaping Future Medicine”.

Visit the Tri-Conference website.

TBI – The Biotechnology Initiative of Toronto, Canada

January 15, 2009 in Toronto, Canada

James McKim, Ph.D. DABT, founder and CSO of CeeTox, will present “The Science of Safety”, an overview of in vitro toxicology, at a breakfast meeting sponsored by TBI-The Biotechnology Initiative of Toronto. The meeting will be held on Thursday, January 15, 2009 at Metro Hall, 55 John Street, Toronto.

Dr. McKim will discuss the use of in vitro data to identify risk and evaluate efficacy, as well as the value of multi-parameter, predictive models in reducing or even replacing the need to test on animals.

Also presenting will be Philip S. Burton, Ph.D., CEO and co-founder of ADMETRx, Inc. CeeTox has been proud to collaborate with ADMETRx, a provider of superior ADME services to promote successul lead selection for in vivo performance. http://www.admetrx.com/

To register or find more information on the meeting, visit The Biotechnology Initiative website.

American College of Toxicology (ACT) 29th Annual Meeting

November 9-12, 2008 in Tucson, AZ

CeeTox will attend the 2008 American College of Toxicology (ACT) Conference at the Hilton El Conquistador in Tucson, Arizona, taking place November 9-12, 2008. CeeTox’s West Coast Business Development Manager, Maryam Famourzadeh, will attend. Look for CeeTox at Booth #29.

Visit the ACT Organization website.

IVTIP Autumn Meeting (In-Vitro Testing Industrial Platform)

Nov. 4-5, 2008 in Brussels, Belgium

CeeTox Founder, Vice-President, and CSO James McKim has been invited to present at the IVTIP Autumn Meeting to be held in Brussels, Belgium, from November 4-5, 2008. Dr. McKim will discuss Building in-vitro alternatives that have in-vivo relevance as part of the Conference theme of reviewing promising tests and new opportunities. The IVTIP (In-Vitro Testing Industrial Platform) is an informal forum of European companies with an active interest in in-vitro regulatory and safety testing. The organization also supports the application, wherever possible, of the principals of the 3Rs: reduce, refine, or replace animal testing. IVTIP members represent companies in the chemical, cosmetics, and pharmaceutical sectors.

Visit the IVTIP website.