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Identifying Cardiotoxic Drugs Using a Two-Cell Model Combined with Multiparametric Analysis: Applications for In Vitro Toxicity Screening
P. Wilga; D. Petrella; A. Swanson; J. Pregenzer; S. Thompson; K. Rutherford-Root; J. McKim
Publication: Society of Toxicology
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Compounds of Different Chemical Classes Elicit Supramaximal Responses In In Vitro Androgen and Estrogen Receptor Mediated Activity Assays
J. Pregenzer; D. Blakeman; J. McKim; V. Wilson; J. Schmid; J. Goldman; G. Earl
Publication: Society of Toxicology
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Anti-Hypercholesterolemia Drugs in the Statin Class Reduce Glutathione Levels and Increase Caspase 3 Activation in an In Vitro Cell Model
J. Pregenzer; J. McKim Jr.; P. Wilga; D. Petrella; A. Swanson
Publication: Society of Toxicology
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Evaluation of a Novel Anti-Tumor Drug Using In Vitro Toxicity Screening in Rat Hepatoma (H4IIE) Cells. Normal Rat Kidney (NRK) Cells, and Rat Primary Hepatocytes
P. Wilga; J. McKim Jr.; J. Pregenzer; D. Petrella; A. Swanson
Publication: Society of Toxicology
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A Biochemical Approach to In Vitro Toxicity Testing
J. McKim; P. Wilga; J. Pregenzer; D. Petrella
Publication: Pharmaceutical Discovery
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Microarray Analysis in Human Hepatocytes Suggests a Mechanism for Hepatotoxicity Induced by Trovafloxacin
M. Liguori; M. Anderson; J, McKim; J. Pregenzer; J. Retief; B. Spear; J. Waring
Publication: Hepatology
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The Value of DNA Methylation Analysis in Basic, Initial Toxicity Assessments
R. Watson; J. McKim; G. Cockerell; J. Goodman
Publication: Toxicological Sciences
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Strategic Importance of Research Support through Pathology
G. Cockerell; J. McKim; S. Vonderfecht
Publication: Toxicologic Pathology
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